Buffalo Bills vs. Carolina Panthers Prediction, Tips & Odds – Dec. 19, 2021

December 19, 2021
nfl predictions

A new round of NFL is being played in the coming days, and our experts have, as always, prepared some very interesting bets just for you. If you like to bet on NFL games, our predictions will interest you without any doubt. Today, Buffalo Bills will host Carolina Panthers in one exciting duel.

We found the best odds for this game at the popular Bet365 sportsbook. You will get an attractive Welcome Bonus for all newly registered customers if you register today. If you wonder how to claim this Bet365 Welcome Bonus, read our article on that subject here

Buffalo Bills

Led by Sean McDermott, the Buffalo Bills have risen to the very top of the AFC. After two decades, they played in the playoffs again, and then they reached the conference finals last season. Over the winter, they further strengthened the team with the goal of reaching the Super Bowl, but at this point, the question is whether they will play in the playoffs at all. When they defeated the Kansas City Chiefs in October, they seemed to be the sovereign rulers of the AFC, but then the team completely fell down.

They experienced a debacle against Jacksonville Jaguars and Indianapolis Colts, and after that, they were defeated by the New England Patriots, their biggest rivals. The team created to fight for the Super Bowl, four weeks before the playoffs is fighting for a place in the Wild Card round. Lose against the Carolina Panthers must not happen, otherwise, the heads could fall in Buffalo.

Carolina Panthers

The situation in the Carolina Panthers is not good. Two years ago, they signed head coach Matt Rhule with the goal to become a contender for the title, but for the second season in a row, they have failed to reach the playoffs. They managed to improve the defense during that period, but the offense that Rhule was in charge of did not work well. They suffered a big blow when the best player Christian McCaffrey was injured, but despite that, they were expected to at least be in the fight for playoffs after they started the season with three wins from three matches.

At this moment, Rhule will try to save his job as more and more people talk and write about the fact that the owner David Tepper could fire him after the last game in the season. The experiment with Cam Newton also did not turn out well and the gray clouds are above this franchise.


Buffalo Bills are at 7-6, while Carolina Panthers are at 5-8. The Bills need three wins from their last four games to play in the playoffs. The Panthers will not be there and all they have to do is try to end the season in the best possible way. These teams last played each other more than four years ago when the Panthers won 9-3 in Carolina.


Buffalo Bills wide receiver Emmanuel Sanders has injured his knee and will not play in this match. Star Lotulelei and Taiwan Jones are questionable. Dion Dawkins has been positive for coronavirus during the week and is unlikely to play.

The Carolina Panthers will not be able to count on cornerback A.J. Bouye due to a foot injury. Christian McCaffrey has been off the field for a long time, and the main wide receiver D.J. Moore is questionable.

Buffalo Bills vs. Carolina Panthers Prediction, Tips & Odds

After an unexpected defeat against the New England Patriots and a failure in overtime in Tampa Bay, the impression is that the Buffalo Bills are so furious that they will throw it all at the Carolina Panthers. The Bills are in urgent mode and a win must be achieved. The Panthers are in such a mode that they are an ideal victim if the Bills are at their maximum from the start and it is to be expected that the home team will win by more than two touchdowns difference.

Prediction: Buffalo Bills -11.5hc
Odds: 1.73
Bookmaker: Bet365

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Author MilosNS

MilosNS is our senior content writer, SEO guru, and first ever tipster who started working with us, and he is still here. He is a well-known name in the sports betting industry, and his knowledge about anything betting related is vast. If you have any questions, or doubts, MilosNS has the answer for you.

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